针对性护理干预在硼替佐米皮下注射治疗多发性骨髓瘤患者中的效果 |
| 粟娟 |
| 川北医学院附属医院，四川南充，637000 |
摘要：目的 分析针对性护理方案用于硼替佐米皮下注射治疗多发性骨髓瘤患者期间对患者治疗期间不良反应发生率、焦虑、抑郁情绪、护理人员操作规范性与确认时间的影响。方法 按照随机抽签的方式将本院于2023 年12 月-2024 年12 月接受临床治疗的100 例硼替佐米皮下注射治疗多发性骨髓瘤患者以分组的方式予以观察，对照组患者主要进行常规护理干预方案，观察组患者则是进行针对性护理干预方案，比较不同护理模式下护理人员操作规范性与确认时间、焦虑与抑郁情绪以及不良反应发生率的发生情况。结果观察组在使用针对性护理干预下可以发现护理人员操作规范性与确认时间指标优于对照组患者的指标（P＜0.05）；患者在焦虑、抑郁评分方面明显低于对照组患者的情绪状态指标（P＜0.05）；而在不良反应发生率方面则明显低于对照组患者的发生情况（P＜0.05）。结论 针对性护理在临床应用期间可以满足患者的不同护理需求，并有效提升硼替佐米皮下注射治疗多发性骨髓瘤患者的治疗效果，还可以提升护理人员在实际操作期间的规范性，并减少治疗后患者不良反应发生率的情况，可在临床进行推广使用。
关健词：硼替佐米皮下注射；多发性骨髓瘤；针对性护理；护理人员操作规范性；不良反应
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Effect of targeted nursing intervention on subcutaneous injection of bortezomib in patients with multiple myeloma |
Juan Su
Affiliated Hospital of North Sichuan Medical College, Nanchong Sichuan 637000, China
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Abstract：Objective To analyze the impact of targeted nursing protocols on adverse reaction incidence, anxiety and depressive symptoms, as well as nursing staff's operational compliance and confirmation time during subcutaneous bortezomib treatment for multiple myeloma patients. Methods A total of 100 patients receiving subcutaneous bortezomib therapy for multiple myeloma at our hospital from December 2023 to December 2024 were randomly assigned into groups for observation. The control group received standard nursing interventions, while the observation group underwent targeted nursing protocols. The study compared nursing staff's operational compliance and confirmation time, anxiety and depressive symptoms, as well as adverse reaction incidence under different care models.Results Under targeted nursing intervention, the observation group demonstrated superior nursing staff compliance and confirmation time metrics compared to the control group (P<0.05). Patients showed significantly lower anxiety and depressive scores (P<0.05) and markedly fewer adverse reactions (P<0.05).Conclusion Targeted nursing effectively meets diverse patient needs during clinical application, enhances treatment efficacy for bortezomib-treated multiple myeloma patients, improves nursing staff's operational standards, reduces post-treatment adverse reactions, and can be clinically promoted for widespread use.
Keywords : Bortezomib subcutaneous injection; multiple myeloma; targeted care; nursing staff operation standardization; adverse reactions
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